Nitrate-Induced Headache in Patients with Stable Angina Pectoris: Beneficial Effect of Starting on a Low Dosage. This is a condition where the heart does not beat as efficiently as it should. A total of 195 drugs are known to interact with isosorbide mononitrate: A total of 330 drugs are known to interact with aspirin: A total of 239 drugs are known to interact with nitroglycerin: No known alcohol/food interactions. Organic Nitrate - an overview | ScienceDirect Topics Available for Android and iOS devices. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. If concomitant therapy cannot be avoided, monitor clinical effects of the . Your doctor may tell you to take a pain reliever to treat your headaches. Unauthorized use of these marks is strictly prohibited. Some side effects may occur that usually do not need medical attention. Conclusions: If you have an eye condition called glaucoma. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Isosorbide is in a class of medications called vasodilators. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not stop taking isosorbide without talking to your doctor. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Isosorbide mononitrate helps to prevent angina chest pain from developing. isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. It can cause your blood pressure to become dangerously low. The dose is according to the body weight and severity of the condition. from the best health experts in the business. Natural Medicines. Background: In the remainder of them there was a highly significant time effect: the overall numbers of headache attacks in the first period of active treatment versus the second were 2,380 vs 1,400 (P < 0.003). Drug interactions may change how your medications work or increase your risk for serious side effects. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Does Alcohol Raise Your Blood Pressure? Natural Medicines. coma (loss of consciousness for a period of time). Prescribed for Angina, Anal Fissure and Epub 2006 Mar 22. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. Isosorbide mononitrate systemic 60 mg (A ID). Take the missed dose as soon as you remember it. Read our editorial policy. Methods: Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. https://naturalmedicines.therapeuticresearch.com. https://naturalmedicines.therapeuticresearch.com. tell your doctor if you are taking or have recently taken riociguat (Adempas) or a phosphodiesterase inhibitor (PDE-5) such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra, Staxyn). The short-acting tablet is usually taken as 10 mg to 40 mg by mouth 2 or 3 times daily with at least a 14 hour period of time per day where you don't take any doses. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. Herbal supplements and heart medicines may not mix - Mayo Clinic Natural remedies for depression: Are they effective? Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. These headaches may be a sign that the medication is working as it should. To view a report comparing 3 (or more) medications, please sign in or create an account. Selected from data included with permission and copyrighted by First Databank, Inc. Valerian: A safe and effective herbal sleep aid? ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. No you may not. Alcohol can make the side effects from isosorbide worse. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. Some conditions may become worse when the drug is suddenly stopped. This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. What happens if I stop taking isosorbide mononitrate (Monoket)? Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. isosorbide mononitrate (Imdur, Ismo, Monoket) - MedicineNet https://naturalmedicines.therapeuticresearch.com. It will not treat an angina attack that has already begun. Sept. 26, 2022. This should pass after a few days. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? Isosorbide mononitrate (Monoket) can cause your blood pressure to drop somewhat. Who should not take Isosorbide Mononitrate? But only about 25% of people who take herbal supplements tell their health care providers. Things to remember when you fill your prescription. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). All rights reserved. AskMayoExpert. Imdur, Monoket (isosorbide mononitrate) dosing, indications - Medscape The Swedish Multicentre Group. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Duplication for commercial use must be authorized by ASHP. Bauer B (expert opinion). Isosorbide: MedlinePlus Drug Information Do not take two doses together to make up for a missed dose. Please see a good cardiologist, get admitted, get checked thoroughly. Unable to load your collection due to an error, Unable to load your delegates due to an error. Alcohol or marijuana (cannabis) can make you more dizzy. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Ginkgo. If we combine this information with your protected Portions of this document last updated: Feb. 01, 2023. If you miss a dose, take it as soon as you remember. As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. It works to relax your blood vessels. It also relaxes and widens blood vessels in your heart (coronary arteries) which increases the flow of blood to your heart muscle. You can consult me online for homeopathic treatment. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. We study 23,548 Isosorbide mononitrate users. All rights reserved. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). Avoid combinations; the risk of the interaction outweighs the benefit. B12 and folic acid is essential along with iron. Isosorbide dinitrate (Isordil): Basics, Side Effects & Reviews - GoodRx Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Bookshelf Herbal supplements can strongly affect the body. Try our Symptom Checker Got any other symptoms? The information on this page is written and peer reviewed by qualified clinicians. Do not take a double dose to make up for a missed one. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Accessed Sept. 7, 2022. (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. Below is the list of medicines, which contains Isosorbide Mononitrate as ingredient. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. https://naturalmedicines.therapeuticresearch.com. Continue to take isosorbide even if you feel well. The extended-release tablet usually is taken once daily in the morning. Never give it to other people even if their condition appears to be the same as yours. Use this medication regularly to get the most benefit from it. information submitted for this request. If you have recently had a head injury or a heart attack. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Clin Res Cardiol. HHS Vulnerability Disclosure, Help Theyre fast, easy-to-use and free! 2023 eHealthMe.com. Do not take more or less of it or take it more often than prescribed by your doctor. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). It works and leaves the body quickly, so it needs to be taken twice a day. What conditions does Isosorbide Mononitrate treat? In Canada - Call your doctor for medical advice about side effects. If you have any problems with the way your liver works, or any problems with the way your kidneys work. Instead, the best way to dispose of your medication is through a medicine take-back program. Nitrates in the management of acute coronary syndrome. In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). To use the sharing features on this page, please enable JavaScript. Contraindications: Isosorbide mononitrate should not be used in cases of acute myocardial infarction with low filling pressure, acute circulatory failure (shock, vascular collapse), or hypertrophic obstructive cardiomyopathy (HOCM), constrictive pericarditis, low cardiac filling pressures, aortic/mitral valve stenosis and diseases associated with a raised intra-cranial pressure e.g following a head trauma and including cerebral haemorrhage. Some products have ingredients that could worsen your heart failure. If you have ever had an allergic reaction to a medicine. This survey is being conducted by the WebMD marketing sciences department. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. We study millions of patients and 5,000 more each day. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or . If you suffer headaches when taking Isosorbide mononitrate, be patient. Do not change the dosing times unless directed by your doctor. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Isosorbide mononitrate: isosorbide mononitrate. Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). Breastfeeding:There is data that nitrates are excreted in breast milk and may cause methemoglobinemia in infants. Zhonghua Yi Xue Za Zhi (Taipei). This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . . Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. This content does not have an Arabic version. Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. US residents can call their local poison control center at 1-800-222-1222. Bethesda, MD 20894, Web Policies Many herbal supplements can interact with prescription drugs. View all By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. Accessed Sept. 7, 2022. Nitroglycerin works very quickly to widen your blood vessels and help your heart pump blood during a heart attack. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. Canada residents can call a provincial poison control center. UpToDate If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate. These side effects may go away during treatment as your body adjusts to the medicine. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. The .gov means its official. Ask your pharmacist any questions you have about refilling your prescription. Some of these interactions can be life-threatening. 8600 Rockville Pike Data were assessed for carryover and time effects. This medicine is available only with your doctor's prescription. It can cause your blood pressure to become dangerously low. information is beneficial, we may combine your email and website usage information with Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Mehta D. Herbal & dietary supplements. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. Isosorbide mononitrate Interactions - Drugs.com "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. 67% of reviewers reported a positive effect, while 13% reported a negative effect. https://naturalmedicines.therapeuticresearch.com. So get a ct scan brain apart from cardiology workup. If this worries you, talk to your doctor or pharmacist about other options. What You Need to Know, Angina (a specific type of chest pain) caused by heart disease. The herb licorice may lower warfarin levels and can add to digoxin's effects. What should I know regarding pregnancy, nursing and administering Isosorbide Mononitrate to children or the elderly? Tachjian A, et al. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). MBBS, MS - General Surgery, mch neuro surgery. Some don't work well with prescription medicines. For haemoglobin formation vit. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Elsevier; 2021. https://www.clinicalkey.com. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Some brands of isosorbide mononitrate tablets should be taken two or three times a day. If you notice other effects not listed above, contact your doctor or pharmacist. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. You may report side effects to the FDA at 1-800-FDA-1088. It works by . Take extra precautions to avoid falling during your treatment with isosorbide. I strongly feel that there is coronary ischemia. Results: Prices for isosorbide mononitrate (Monoket) start at just $29.86 with a GoodRx coupon. Isosorbide Mononitrate ER Oral: Uses, Side Effects - WebMD Isosorbide mononitrate and isosorbide dinitrate - NHS Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. The use of the Truven Health products is at your sole risk.